UPDATE 2-J&J bladder drug needs stronger caution-FDA staff

(Reuters) - WASHINGTON, April 9 - Johnson & Johnson's bladder drug Ditropan needs stronger cautions about the risk of hallucination and similar problems in children and older patients, U.S. Food and Drug Administration staff said in documents released on Monday.

The drug, also known as oxybutynin, already lists insomnia, nervousness, confusion and other central nervous system risks on its label, but staff reviewers said more explicit cautions are needed.


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AMD sees revenue shortfall, cuts spending plans

(Reuters) - "AMD is signaling that it is focusing more on nearer-term profitability as opposed to targeting market share," said JoAnne Feeney, managing director with FTN Midwest Securities.

"People were concerned about that strategy," Feeney said.


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UPDATE 1-U.S. winter wheat farmers fret after weekend freeze

(Reuters) - KANSAS CITY, Mo., April 9 - A mild winter and a wet and warm start to spring had many U.S. wheat industry players predicting a bountiful summer harvest.

But that changed over the weekend when unseasonable freezing temperatures blanketed the U.S. Plains and Midwest winter wheat growing areas, killing off some of the rapidly maturing plants.


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UPDATE 2-NextWave Wireless to buy IPWireless

(Reuters) - NEW YORK, April 9 - NextWave Wireless Inc. said it will buy privately held IPWireless Inc. for about $100 million in cash and stock, giving it technology to support a new generation of mobile broadband networks.

NextWave, a wireless technology developer and owner of wireless airwaves, said it could pay another $135 million in cash and stock based on the achievement of certain revenue milestones in 2007 to 2009.


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UPDATE 1-Boston Scientific notifies doctors of ICD battery issue

(Reuters) - CHICAGO, April 9 - Boston Scientific Corp. has notified doctors that some of its implantable heart defibrillators contain batteries that could deplete early, shortening the life span of the devices.

There have been no patient deaths or serious injuries associated with the battery voltage problem, the company said in a letter to doctors dated April 5 and posted on the Web site of its Guidant unit.


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Proxy firm urges Genesis investors to reject deal

(Reuters) - Genesis, which agreed in January to be acquired by Formation Capital LLC and JER Partners for $63 per share, said it strongly disagreed with ISS's recommendation.

"In recommending a vote against the proposal, ISS is asking shareholders to forego the certainty of a $63 all-cash offer for the uncertainty of an unknown alternative," Genesis said in a statement.


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US STOCKS-Indexes end flat on deals; Dow Chemical denies talk

(Reuters) - NEW YORK, April 9 - U.S. stocks closed flat on Monday as news that billionaire investor Warren Buffett had bought stakes in the railroad sector and strong jobs data offset worries about earnings and subprime loans.

The transport sector rallied after Buffett acquired a stake in three railroad companies in a vote of confidence for not only railroads, but the economy. Shares of Burlington Northern Santa Fe Corp. jumped after Buffett's Berkshire Hathaway Inc. said it acquired a 10.9 percent stake in the company to become its largest shareholder.

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